Travaux en cours

Elaboration d'intervalles de référence pour les variables du syndrome métabolique chez l'enfant et sur les données d'absorptiométrie osseuse

Etude et validation d'indicateurs de qualité pour la prise en charge en obstétrique

Suivi de cohortes d'enfants atteints de maladie chronique

Essais thérapeutiques dans les maladies rares de l'enfant

Etude des facteurs liés au recrutement des enfants dans les études cliniques

Autres activités

Enseignement à l'UFR de médecine Bichat - Saint Louis - Lariboisière, Université Paris VII Accueil de doctorants pour l' ÉCOLE DOCTORALE 393 SANTÉ PUBLIQUE : ÉPIDÉMIOLOGIE ET SCIENCES DE L'INFORMATION BIOMÉDICALE, Directeur : Alain-Jacques Valleron Formation des étudiants en traitement des données et statistiques



Hopital Robert Debré

48 boulevard Sérurier

75019 PARIS

01 40 03 24 65



1. See, H., Lachenaud, J., Alberti, C., Mariani-Kurkdjian, P., Aujard, Y. and Baud, O. Outcome of very preterm infants with Mycoplasma/Ureaplasma airway colonization treated with josamycine. Acta Paediatr, 2010.

2. Henriet, S., Kaguelidou, F., Bidet, P., Lorrot, M., De Lauzanne, A., Dauger, S., Angoulvant, F., Mercier, J.C., Alberti, C., Bingen, E. and Faye, A. Invasive group A streptococcal infection in children: clinical manifestations and molecular characterization in a French pediatric tertiary care center. Eur J Clin Microbiol Infect Dis, 2010.


3. Tilea, B., Alberti, C., Adamsbaum, C., Armoogum, P., Oury, J.F., Cabrol, D., Sebag, G., Kalifa, G. and Garel, C. Cerebral biometry in fetal magnetic resonance imaging: new reference data. Ultrasound Obstet Gynecol, 2009. 33(2): 173-181.

4. Mok, E., Letellier, G., Cuisset, J.M., Denjean, A., Gottrand, F., Alberti, C. and Hankard, R. Lack of functional benefit with glutamine versus placebo in Duchenne muscular dystrophy: a randomized crossover trial. PLoS One, 2009. 4(5): e5448.

5. Malekzadeh, F., Alberti, C., Nouraei, M., Vahedi, H., Zaccaria, I., Meinzer, U., Nasseri-Moghaddam, S., Sotoudehmanesh, R., Momenzadeh, S., Khaleghnejad, R., Rashtak, S., Olfati, G., Malekzadeh, R. and Hugot, J.P. Crohn's disease and early exposure to domestic refrigeration. PLoS ONE, 2009. 4(1): e4288.

6. Leroy, V., Baudouin, V., Alberti, C., Guest, G., Niaudet, P., Loirat, C., Deschenes, G., Czernichow, P. and Simon, D. Growth in boys with idiopathic nephrotic syndrome on long-term cyclosporin and steroid treatment. Pediatr Nephrol, 2009.

7. Guinard-Samuel, V., Bonnard, A., De Lagausie, P., Philippe-Chomette, P., Alberti, C., El Ghoneimi, A., Peuchmaur, M. and Berrebi-Binczak, D. Calretinin immunohistochemistry: a simple and efficient tool to diagnose Hirschsprung disease. Mod Pathol, 2009. 8. Dossou-Yovo, O.P., Zaccaria, I., Benkerrou, M., Hauchecorne, M., Alberti, C., Rahimy, M.C., Elion, J. and Lapoumeroulie, C. Effects of RANTES and MBL2 gene polymorphisms in sickle cell disease clinical outcomes: association of the g.In1.1T>C RANTES variant with protection against infections. Am J Hematol, 2009. 84(6): 378-80.

9. Denamur, E., Delezoide, A.L., Alberti, C., Bourillon, A., Gubler, M.C., Bouvier, R., Pascaud, O., Elion, J., Grandchamp, B., Michel-Calemard, L., Missy, P., Zaccaria, I., Le Nagard, H., Gerard, B. and Loirat, C. Genotype-phenotype correlations in fetuses and neonates with autosomal recessive polycystic kidney disease. Kidney Int, 2009. 10. Caro, V., Guiso, N., Alberti, C., Liguori, S., Burucoa, C., Couetdic, G., Doucet-Populaire, F., Ferroni, A., Papin-Gibaud, S., Grattard, F., Reglier-Poupet, H., Raymond, J., Soler, C., Bouchet, S., Charreau, S., Couzon, B., Leymarie, I., Tavares, N., Choux, M., Bingen, E. and Bonacorsi, S. Proficiency program for real-time PCR diagnosis of Bordetella pertussis infections in French hospital laboratories and at the French National Reference Center for whooping cough and other bordetelloses. J Clin Microbiol, 2009.

11. Bonnard, A., Carricaburu, E., Alberti, C., Maury, L., Saizou, C., El Ghoneimi, A. and Dauger, S. Is intraabdominal pressure a good predictor of mortality in necrotizing enterocolitis? Intensive Care Med, 2009.

12. Bader-Meunier, B., Verlhac, S., Elmaleh-Berges, M., Ithier, G., Sellami, F., Faid, S., Missud, F., Ducrocq, R., Alberti, C., Zaccaria, I., Baruchel, A. and Benkerrou, M. Effect of transfusion therapy on cerebral vasculopathy in children with sickle-cell anemia. Haematologica, 2009. 94(1): 123-6.

13. Autret-Leca, E., Bauer, S., Alberti, C., Jonville-Bera, A.P., Aujard, Y., Bensouda-Grimaldi, L. and Baud, O. [Glucocorticoide therapy in premature infants: French practices in 2006]. Arch Pediatr, 2009. 16(7): 999-1004.


14. Sarhan, O., Zaccaria, I., Macher, M.A., Muller, F., Vuillard, E., Delezoide, A.L., Sebag, G., Oury, J.F., Aigrain, Y. and El-Ghoneimi, A. Long-term outcome of prenatally detected posterior urethral valves: single center study of 65 cases managed by primary valve ablation. J Urol, 2008. 179(1): 307-12; discussion 312-3.

15. Odievre, M.H., Bony, V., Benkerrou, M., Lapoumeroulie, C., Alberti, C., Ducrocq, R., Jacqz-Aigrain, E., Elion, J. and Cartron, J.P. Modulation of erythroid adhesion receptor expression by hydroxyurea in children with sickle cell disease. Haematologica, 2008. 93(4): 502-10.

16. Meinzer, U., Esmiol-Welterlin, S., Barreau, F., Berrebi, D., Dussaillant, M., Bonacorsi, S., Chareyre, F., Niwa-Kawakita, M., Alberti, C., Sterkers, G., Villard, C., Lesuffleur, T., Peuchmaur, M., Karin, M., Eckmann, L., Giovannini, M., Ollendorff, V., Wolf-Watz, H. and Hugot, J.P. Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice. PLoS ONE, 2008. 3(7): e2769.

17. Meas, T., Deghmoun, S., Armoogum, P., Alberti, C. and Levy-Marchal, C. Consequences of being born small for gestational age on body composition: an 8-year follow-up study. J Clin Endocrinol Metab, 2008. 93(10): 3804-9.

18. Kaguelidou, F., Alberti, C., Castanet, M., Guitteny, M.A., Czernichow, P. and Leger, J. Predictors of autoimmune hyperthyroidism relapse in children after discontinuation of antithyroid drug treatment. J Clin Endocrinol Metab, 2008. 93(10): 3817-26.

19. Durand-Zaleski, I.S., Alberti, C., Durieux, P., Duval, X., Gottot, S., Ravaud, P., Gainotti, S., Vincent-Genod, C., Moreau, D. and Amiel, P. Informed consent in clinical research in France: assessment and factors associated with therapeutic misconception. J Med Ethics, 2008. 34(9): e16.

20. Druet, C., Baltakse, V., Chevenne, D., Dorgeret, S., Zaccaria, I., Wang, Y. and Levy-Marchal, C. Independent effect of visceral adipose tissue on metabolic syndrome in obese adolescents. Horm Res, 2008. 70(1): 22-8.

21. Beydon, N., M'Buila, C., Peiffer, C., Bernard, A., Zaccaria, I. and Denjean, A. Can bronchodilator response predict bronchial response to methacholine in preschool coughers? Pediatr Pulmonol, 2008. 43(8): 815-21.

22. Berrebi, D., Leclerc, J., Schleiermacher, G., Zaccaria, I., Boccon-Gibod, L., Fabre, M., Jaubert, F., El Ghoneimi, A., Jeanpierre, C. and Peuchmaur, M. High cyclin E staining index in blastemal, stromal or epithelial cells is correlated with tumor aggressiveness in patients with nephroblastoma. PLoS ONE, 2008. 3(5): e2216.

23. Barat, P., Valade, A., Brosselin, P., Alberti, C., Maurice-Tison, S. and Levy-Marchal, C. The growing incidence of type 1 diabetes in children: The 17-year French experience in Aquitaine. Diabetes Metab, 2008.

24. Autret-Leca, E., Bauer, S., Alberti, C., Jonville-Bera, A.P., Aujard, Y., Bensouda-Grimaldi, L. and Baud, O. Postnatal glucocorticoids in preterm neonates: use in French neonatal centres in 2006. Arch Dis Child Fetal Neonatal Ed, 2008. 93(5): F398.

25. Angoulvant, F., Llor, J., Alberti, C., Kheniche, A., Zaccaria, I., Garel, C. and Dauger, S. Inter-observer variability in chest radiograph reading for diagnosing acute lung injury in children. Pediatr Pulmonol, 2008. 43(10): 987-91.


26. Sznajer, Y., Keren, B., Baumann, C., Pereira, S., Alberti, C., Elion, J., Cave, H. and Verloes, A. The spectrum of cardiac anomalies in Noonan syndrome as a result of mutations in the PTPN11 gene. Pediatrics, 2007. 119(6): e1325-31.

27. Sellier-Leclerc, A.L., Fremeaux-Bacchi, V., Dragon-Durey, M.A., Macher, M.A., Niaudet, P., Guest, G., Boudailliez, B., Bouissou, F., Deschenes, G., Gie, S., Tsimaratos, M., Fischbach, M., Morin, D., Nivet, H., Alberti, C. and Loirat, C. Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome. J Am Soc Nephrol, 2007. 18(8): 2392-400.

28. Roze, C., Doyen, C., Le Heuzey, M.F., Armoogum, P., Mouren, M.C. and Leger, J. Predictors of late menarche and adult height in children with anorexia nervosa. Clin Endocrinol (Oxf), 2007. 67(3): 462-7.

29. Leger, J., Mercat, I., Alberti, C., Chevenne, D., Armoogum, P., Tichet, J. and Czernichow, P. The relationship between the GH/IGF-I axis and serum markers of bone turnover metabolism in healthy children. Eur J Endocrinol, 2007. 157(5): 685-692.

30. Hugot, J.P., Zaccaria, I., Cavanaugh, J., Yang, H., Vermeire, S., Lappalainen, M., Schreiber, S., Annese, V., Jewell, D.P., Fowler, E.V., Brant, S.R., Silverberg, M.S., Cho, J., Rioux, J.D., Satsangi, J. and Parkes, M. Prevalence of CARD15/NOD2 mutations in Caucasian healthy people. Am J Gastroenterol, 2007. 102(6): 1259-67.

31. Falip, C., Blanc, N., Maes, E., Zaccaria, I., Oury, J.F., Sebag, G. and Garel, C. Postnatal clinical and imaging follow-up of infants with prenatal isolated mild ventriculomegaly: a series of 101 cases. Pediatr Radiol, 2007. 37(10): 981-9.

32. Dossou-Yovo, O.P., Lapoumeroulie, C., Hauchecorne, M., Zaccaria, I., Ducrocq, R., Krishnamoorthy, R., Rahimy, M.C. and Elion, J. Variants of the mannose-binding lectin gene in the Benin population: heterozygosity for the p.G57E allele may confer a selective advantage. Hum Biol, 2007. 79(6): 687-97.

33. Beydon, N., M'Buila, C., Bados, A., Peiffer, C., Bernard, A., Zaccaria, I. and Denjean, A. Interrupter resistance short-term repeatability and bronchodilator response in preschool children. Respir Med, 2007. 101(12): 2482-7.

34. Amiel, P., Moreau, D., Vincent-Genod, C., Alberti, C., Hankard, R., Ravaud, P., Gottot, S. and Gaultier, C. Noninvitation of eligible individuals to participate in pediatric studies: a qualitative study. Arch Pediatr Adolesc Med, 2007. 161(5): 446-50.


35. Pedron, B., Yakouben, K., Guerin, V., Borsali, E., Auvrignon, A., Landman, J., Alberti, C., Leverger, G., Baruchel, A. and Sterkers, G. HLA alleles and haplotypes in French North African immigrants. Hum Immunol, 2006. 67(7): 540-50.

36. Munck, A., Gerardin, M., Alberti, C., Ajzenman, C., Lebourgeois, M., Aigrain, Y. and Navarro, J. Clinical outcome of cystic fibrosis presenting with or without meconium ileus: a matched cohort study. J Pediatr Surg, 2006. 41(9): 1556-60.

37. Leger, J., Marinovic, D., Alberti, C., Dorgeret, S., Chevenne, D., Marchal, C.L., Tubiana-Rufi, N., Sebag, G. and Czernichow, P. Lower bone mineral content in children with type 1 diabetes mellitus is linked to female sex, low IGFI levels and high insulin requirement. J Clin Endocrinol Metab, 2006.

38. Garel, C. and Alberti, C. Coronal measurement of the fetal lateral ventricles: comparison between ultrasonography and magnetic resonance imaging. Ultrasound Obstet Gynecol, 2006. 27(1): 23-7.

39. Druet, C., Dabbas, M., Baltakse, V., Payen, C., Jouret, B., Baud, C., Chevenne, D., Ricour, C., Tauber, M., Polak, M., Alberti, C. and Levy-Marchal, C. Insulin resistance and the metabolic syndrome in obese French children. Clin Endocrinol (Oxf), 2006. 64(6): 672-8.

40. Bui, T., Daire, J.L., Chalard, F., Zaccaria, I., Alberti, C., Elmaleh, M., Garel, C., Luton, D., Blanc, N. and Sebag, G. Microstructural development of human brain assessed in utero by diffusion tensor imaging. Pediatr Radiol, 2006.

41. Alison, M., Dorgeret, S., Marinovic, D., Alberti, C., Leger, J., Czernichow, P. and Sebag, G. [Pediatric prediction models for evaluation of bone mass with DEXA]. Arch Pediatr, 2006. 13(6): 780-1.


42. Trang, H., Dehan, M., Beaufils, F., Zaccaria, I., Amiel, J. and Gaultier, C. The French Congenital Central Hypoventilation Syndrome Registry: general data, phenotype, and genotype. Chest, 2005. 127(1): 72-9.

43. Prot, S., Fontan, J.E., Alberti, C., Bourdon, O., Farnoux, C., Macher, M.A., Foureau, A., Faye, A., Beaufils, F., Gottot, S. and Brion, F. Drug administration errors and their determinants in pediatric in-patients. Int J Qual Health Care, 2005.

44. Meinzer, U., Idestrom, M., Alberti, C., Peuchmaur, M., Belarbi, N., Bellaiche, M., Mougenot, J.F., Cezard, J.P., Finkel, Y. and Hugot, J.P. Ileal involvement is age dependent in pediatric Crohn's disease. Inflamm Bowel Dis, 2005. 11(7): 639-44.

45. Marinovic, D., Dorgeret, S., Lescoeur, B., Alberti, C., Noel, M., Czernichow, P., Sebag, G., Vilmer, E. and Leger, J. Improvement in bone mineral density and body composition in survivors of childhood acute lymphoblastic leukemia: a 1-year prospective study. Pediatrics, 2005. 116(1): e102-8.

46. Lucidarme, N., Alberti, C., Zaccaria, I., Claude, E. and Tubiana-Rufi, N. Alternate-site testing is reliable in children and adolescents with type 1 diabetes, except at the forearm for hypoglycemia detection. Diabetes Care, 2005. 28(3): 710-1.

47. Fakhoury, M., Litalien, C., Medard, Y., Cave, H., Ezzahir, N., Peuchmaur, M. and Jacqz-Aigrain, E. Localization and mRNA expression of CYP3A and P-glycoprotein in human duodenum as a function of age. Drug Metab Dispos, 2005. 33(11): 1603-7.

48. Ezzahir, N., Alberti, C., Deghmoun, S., Zaccaria, I., Czernichow, P., Levy-Marchal, C. and Jaquet, D. Time course of catch-up in adiposity influences adult anthropometry in individuals who were born small for gestational age. Pediatr Res, 2005. 58(2): 243-7.


49. Bourges, O., Dorgeret, S., Alberti, C., Hugot, J.P., Sebag, G. and Cezard, J.P. [Low bone mineral density in children with Crohn's disease]. Arch Pediatr, 2004. 11(7): 800-6.


50. Hugot, J.P., Alberti, C., Berrebi, D., Bingen, E. and Cezard, J.P. Crohn's disease: the cold chain hypothesis. Lancet, 2003. 362(9400): 2012-5.

51. Haddad, E., Moura, I.C., Arcos-Fajardo, M., Macher, M.A., Baudouin, V., Alberti, C., Loirat, C., Monteiro, R.C. and Peuchmaur, M. Enhanced Expression of the CD71 Mesangial IgA1 Receptor in Berger Disease and Henoch-Schonlein Nephritis: Association between CD71 Expression and IgA Deposits. J Am Soc Nephrol, 2003. 14(2): 327-37.

52. Bridge, P.D., McKenzie, S.A., Beydon, N., Alberti, C. and Gaultier, C. Time for standardization. Am J Respir Crit Care Med, 2003. 167(4): 666.

53. Beydon, N., Pin, I., Matran, R., Chaussain, M., Boule, M., Alain, B., Bellet, M., Amsallem, F., Alberti, C., Denjean, A. and Gaultier, C. Pulmonary function tests in preschool children with asthma. Am J Respir Crit Care Med, 2003. 168(6): 640-4. Epub 2003 Jul 17.

54. Benoist, J.F., Alberti, C., Leclercq, S., Rigal, O., Jean-Louis, R., Ogier De Baulny, H., Porquet, D. and Biou, D. Cerebrospinal Fluid Lactate and Pyruvate Concentrations and Their Ratio in Children: Age-related Reference Intervals. Clin Chem, 2003. 49(3): 487-94.


55. Cezard, J.P., Touati, G., Alberti, C., Hugot, J.P., Brinon, C. and Czernichow, P. Growth in paediatric Crohn's disease. Horm Res, 2002. 58(Suppl 1): 11-5.

56. Beydon, N., Amsallem, F., Bellet, M., Boule, M., Chaussain, M., Denjean, A., Matran, R., Wuyam, B., Alberti, C. and Gaultier, C. Pre/postbronchodilator interrupter resistance values in healthy young children. Am J Respir Crit Care Med, 2002. 165(10): 1388-94.

57. Beydon, N., Amsallem, F., Bellet, M., Boule, M., Chaussain, M., Denjean, A., Matran, R., Pin, I., Alberti, C. and Gaultier, C. Pulmonary function tests in preschool children with cystic fibrosis. Am J Respir Crit Care Med, 2002. 166(8): 1099-104.